James L Mills Selected Research

Formate-Tetrahydrofolate Ligase

4/2009	Analysis of the MTHFD1 promoter and risk of neural tube defects.
11/2002	A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

James L Mills Research Topics

Disease

31	Neural Tube Defects (Exencephaly) 01/2021 - 11/2002
9	Neoplasms (Cancer) 01/2019 - 04/2004
5	Autism Spectrum Disorder 01/2022 - 08/2007
5	Pre-Eclampsia (Preeclampsia) 06/2021 - 06/2012
5	Gestational Diabetes (Gestational Diabetes Mellitus) 11/2019 - 12/2014
4	Congenital Abnormalities (Deformity) 11/2010 - 11/2002
3	Type 2 Diabetes Mellitus (MODY) 02/2022 - 01/2007
3	Inflammation (Inflammations) 02/2022 - 01/2016
3	Obesity 02/2022 - 02/2009
3	Infertility (Sterility) 01/2020 - 11/2011
3	Anovulation 01/2020 - 01/2017
3	Premature Birth (Birth, Premature) 10/2019 - 12/2014
3	Spinal Dysraphism (Spina Bifida) 02/2014 - 06/2007
3	Anemia 07/2011 - 06/2003
3	Abruptio Placentae (Placental Abruption) 09/2008 - 02/2005
2	Pituitary ACTH Hypersecretion 01/2019 - 01/2017
2	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 01/2018 - 06/2008
2	Pulmonary Valve Stenosis (Pulmonary Stenosis) 01/2017 - 06/2010
2	Cleft Palate (Palate, Cleft) 09/2013 - 09/2008
2	Umbilical Hernia (Omphalocele) 05/2012 - 07/2005
2	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 10/2011 - 04/2004
2	Autistic Disorder (Autism) 05/2008 - 08/2007
2	Spontaneous Abortion (Miscarriage) 07/2005 - 10/2002
2	Pregnancy Complications 07/2005 - 03/2002
1	Prediabetic State (Prediabetes) 02/2022
1	Stillbirth 01/2022
1	Hypersensitivity (Allergy) 01/2021
1	Exanthema (Rash) 01/2021
1	Confusion (Bewilderment) 01/2020
1	Nausea 01/2020
1	Pain (Aches) 01/2020
1	Congenital Hypothyroidism (Cretinism) 01/2020
1	Vomiting 01/2020
1	Fatty Liver 11/2019
1	Insulin Resistance 05/2018
1	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2018
1	Female Infertility 01/2018
1	Carney Complex 07/2017
1	Noonan Syndrome (Female Pseudo-Turner Syndrome) 01/2017
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 05/2016
1	Bone Fractures (Bone Fracture) 09/2015

Drug/Important Bio-Agent (IBA)

44	Folic Acid (Vitamin M)FDA LinkGeneric 01/2022 - 01/2002
13	HomocysteineIBA 01/2020 - 01/2002
9	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 05/2016 - 03/2002
8	EnzymesIBA 05/2012 - 01/2002
6	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 08/2013 - 01/2002
5	Biomarkers (Surrogate Marker)IBA 02/2022 - 12/2014
5	IodineIBA 01/2022 - 01/2019
4	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 06/2012
4	VitaminsIBA 05/2012 - 06/2003
3	LipidsIBA 02/2022 - 08/2013
3	ORALIT (ORS)IBA 01/2022 - 06/2010
3	Hormones (Hormone)IBA 01/2020 - 08/2007
3	Choline (Choline Chloride)IBA 10/2014 - 11/2011
3	Transcription Factors (Transcription Factor)IBA 01/2013 - 06/2012
3	Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)IBA 04/2009 - 11/2002
2	Glucose (Dextrose)FDA LinkGeneric 02/2022 - 01/2020
2	Insulin (Novolin)FDA Link 02/2022 - 01/2020
2	IodidesIBA 01/2022 - 10/2019
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 06/2021 - 10/2019
2	Thyroglobulin FDA Link 06/2021 - 10/2019
2	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 01/2021 - 06/2007
2	Vitamin D FDA LinkGeneric 01/2021 - 05/2018
2	C-Reactive ProteinIBA 01/2021 - 01/2016
2	Vitamin B Complex (B Vitamins)IBA 01/2020 - 09/2015
2	ZincIBA 01/2020 - 01/2020
2	AndrogensIBA 01/2018 - 06/2010
2	Messenger RNA (mRNA)IBA 07/2017 - 12/2009
2	CalciumIBA 06/2017 - 12/2014
2	Proteins (Proteins, Gene)FDA Link 04/2013 - 10/2008
2	Growth Hormone (Somatotropin)IBA 10/2011 - 04/2004
2	Formate-Tetrahydrofolate LigaseIBA 04/2009 - 11/2002
2	Methenyltetrahydrofolate CyclohydrolaseIBA 04/2009 - 11/2002
2	Reduced Folate Carrier ProteinIBA 04/2006 - 07/2005
2	Transcobalamins (Transcobalamin II)IBA 07/2005 - 04/2005
2	methionine synthase reductaseIBA 07/2005 - 01/2002
1	Dihydrotachysterol (AT 10)IBA 06/2021
1	25-hydroxyvitamin DIBA 01/2021
1	SaltsIBA 01/2020
1	C-PeptideIBA 01/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2019
1	TransferasesIBA 11/2019
1	Alanine Transaminase (SGPT)IBA 11/2019
1	Indicators and Reagents (Reagents)IBA 11/2019
1	formic acid (formate)IBA 01/2018
1	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 06/2017
1	cholesterylphosphorylethylpyridiniumIBA 06/2017
1	Triglycerides (Triacylglycerol)IBA 06/2017
1	Progesterone FDA LinkGeneric 01/2017
1	Ubiquitin-Specific ProteasesIBA 01/2017
1	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2017
1	A-factor (Streptomyces)IBA 01/2017
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2017
1	antineoplaston A10 (A 10)IBA 01/2017
1	Proton-Coupled Folate TransporterIBA 04/2016
1	PyridoxalIBA 01/2016
1	NeopterinIBA 01/2016
1	KynurenineIBA 01/2016
1	Tryptophan (L-Tryptophan)FDA Link 01/2016

Therapy/Procedure

2	Therapeutics 06/2004 - 04/2004